⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15870993 | 0.78 | GRM5 (0.68) | — | |
| SCHEMBL201781 | 0.74 | — | — | |
| SCHEMBL577167 | 0.74 | — | — | |
| SCHEMBL1930368 | 0.74 | — | — | |
| SCHEMBL1007610 | 0.74 | — | — | |
| SCHEMBL2848719 | 0.74 | — | — | |
| Methane SCHEMBL27549579 | 0.72 | — | — | |
| SCHEMBL19778794 | 0.70 | — | — | |
| SCHEMBL5805253 | 0.70 | — | — | |
| SCHEMBL28748970 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023190015-A1 | 1-ARYL TETRAHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE OR SALT THEREOF, PESTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | 日本農薬株式会社 | 2023-10-05 | — | — | WO | claimed |
| WO-2023127805-A1 | ARYL TETRAHYDROPYRIDAZINE DERIVATIVE OR SALT THEREOF, PESTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | 日本農薬株式会社 | 2023-07-06 | — | — | WO | claimed |
| CN-109810110-B | Compound with 2-aminopyrimidine structure, preparation method and application thereof | 中国科学院上海药物研究所 | 2023-01-24 | — | — | CN | claimed |
| CN-115433203-A | Amine fluorinated curcumenol derivative compound and application and preparation method thereof | 华东理工大学 | 2022-12-06 | — | — | CN | claimed |
| CN-115260282-A | Novel coronavirus main protease inhibitor and preparation method and application thereof | 天津国际生物医药联合研究院 | 2022-11-01 | — | — | CN | claimed |
| US-11332464-B2 | Inhibitors of lysine gingipain | Cortexyme, Inc. (US) | 2022-05-17 | — | — | US | claimed |
| CN-107074801-B | Aryl and arylalkyl substituted pyrazolyl and pyrimidinyl tricyclenones as antioxidant inflammatory modulators | 里亚塔医药公司 | 2021-11-05 | — | — | CN | claimed |
| EP-3774750-A1 | IMMUNOMODULATORS, COMPOSITIONS AND METHODS THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-02-17 | — | — | EP | claimed |
| US-20210017167-A1 | INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2021-01-21 | — | — | US | claimed |
| EP-3204352-B1 | INHIBITORS OF LYSINE GINGIPAIN | CORTEXYME INC (US) | 2020-07-01 | — | — | EP | claimed |
| WO-1997009319-A1 | SUBSTITUTED 1-AMINO-3-PHENYLURACIL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | claimed |
| US-5512588-A | ANTIULCER AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-30 | — | — | US | claimed |
| WO-1995034540-A1 | BENZOHETEROCYCLIC DERIVATIVES USEFUL AS VASOPRESSIN OR OXYTOCIN MODULATORS | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-12-21 | — | — | WO | claimed |
| US-5138064-A | Chemical intermediate for penicillin derivative | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1992-08-11 | — | — | US | claimed |
| EP-0180188-B1 | A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-15 | — | — | EP | claimed |
| EP-0402150-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | claimed |
| EP-0402155-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | claimed |
| EP-0059146-B1 | MEDICAMENTS DERIVED FROM 3-HYDROXY DODECAHYDRO BENZ(E) INDEN-7-ON, PRODUCTS DERIVED FROM 3-HYDROXY DODECAHYDRO BENZ(E) INDEN-7-ON AND PROCESS FOR THEIR PREPARATION | ROUSSEL-UCLAF (FR) | 1985-09-25 | — | — | EP | claimed |
| US-4472386-A | 5-Fluoro-(β-uridine or 2'-deoxy-β-uridine) derivatives, a process for producing the same and a carcinostatic agent containing the same | TOYAMA CHEMICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | claimed |
| US-4317825-A | WATER SOLUBILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-02 | — | — | US | claimed |