Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 7/20 | 0.48 |
| ▸ | MMP9 | P14780 | 7/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1735671 | 0.88 | POLB (0.51) | POLBSMN1; SMN2MMP2MMP9ADAMTS4 | |
| SCHEMBL1737163 | 0.88 | POLB (0.51) | POLBSMN1; SMN2MMP2MMP9ADAMTS4 | |
| SCHEMBL28768450 | 0.86 | CA2 (0.51) | SMN1; SMN2MMP2MMP9MEN1KMT2A | |
| SCHEMBL31064911 | 0.86 | POLB (0.50) | POLBSMN1; SMN2MMP2MMP9ADAMTS4 | |
| SCHEMBL7315790 | 0.86 | POLB (0.50) | POLBMMP2MMP9ADAMTS4MEN1 | |
| SCHEMBL31128480 | 0.86 | ADAMTS4 (0.55) | POLBMMP2MMP9ADAMTS4MEN1 | |
| SCHEMBL7397814 | 0.86 | POLB (0.50) | POLBMMP2MMP9ADAMTS4MEN1 | |
| SCHEMBL1403263 | 0.85 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL8147112 | 0.85 | SMN1; SMN2 (0.52) | POLBSMN1; SMN2MMP2MMP9MMP8 | |
| SCHEMBL10076154 | 0.85 | MMP2 (0.59) | SMN1; SMN2MMP2MMP9ADAMTS4MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093231-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | TELIK, INC. | 2008-02-14 | — | — | US | disclosed |
| US-7262182-B2 | Sulfonylethyl phosphorodiamidates | TELIK, INC. (US) | 2007-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039429-A1 | SULFONYLETHYL PHOSPHORODIAMIDATES | MTAP, TYMP, PHOSPHO1 | POLB 3723/4885SMN1; SMN2 1097/4885MMP2 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.