Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1837915 | 0.88 | LTA4H (0.60) | ESR1ESR2ACHEMAPTNPC1 | |
| SCHEMBL5075258 | 0.84 | CNR2 (0.52) | SRD5A2ESR1ACHECNR2SMN1; SMN2 | |
| SCHEMBL31012104 | 0.82 | MAPT (0.71) | SRD5A2ESR1ESR2PARP10MAPT | |
| SCHEMBL8071074 | 0.82 | MAPT (0.71) | SRD5A2ESR1ESR2PARP10MAPT | |
| SCHEMBL9861628 | 0.82 | PLK1 (0.64) | ESR1ESR2CNR2MAPTNPC1 | |
| SCHEMBL3471102 | 0.82 | MAPT (0.71) | SRD5A2ESR1ESR2PARP10MAPT | |
| SCHEMBL10486226 | 0.82 | MAPT (0.71) | SRD5A2ESR1ESR2PARP10MAPT | |
| SCHEMBL10014123 | 0.81 | RAB9A (0.58) | ACHECNR2MAPTNPC1RAB9A | |
| SCHEMBL25175254 | 0.81 | MAPT (0.68) | SRD5A2MAPTRAB9AHPGDTHRB | |
| SCHEMBL19328239 | 0.81 | SRD5A2 (0.62) | SRD5A2PARP10MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001131-A1 | METHOD OF MAKING POLY(ARYL ETHER KETONES) FROM 4,4' DIFLUOROBENZOPHENONE COMPRISING OXIDIZING SPECIES AND/OR NITRO COMPOUNDS | SOLVAY SPECIALTY POLYMERS USA, L.L.C. (US) | 2012-01-05 | — | — | WO | disclosed |