SCHEMBL3471102

SCHEMBL3471102

O=C(c1ccc(O)cc1)c1ccc(Oc2ccc(C(=O)c3ccc(O)cc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.71
ESR1 P03372 2/20 0.71
ESR2 Q92731 2/20 0.71
HPGD P15428 2/20 0.71
LMNA P02545 2/20 0.71
PKM P14618 1/20 0.71
HTT P42858 1/20 0.71
PARP10 Q53GL7 2/20 0.69
KMT2A Q03164 3/20 0.67
MEN1 O00255 2/20 0.67
SRD5A2 P31213 4/20 0.61
ELANE P08246 1/20 0.60
MAPK1 P28482 1/20 0.58
LTA4H P09960 2/20 0.56
NR1H2 P55055 1/20 0.56
BAX Q07812 1/20 0.56
RAB9A P51151 2/20 0.54
ALDH1A1 P00352 1/20 0.54
PARP15 Q460N3 1/20 0.54
PARP14 Q460N5 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10486226 1.00 MAPT (0.71) MAPTESR1ESR2HPGDLMNA
SCHEMBL31012104 1.00 MAPT (0.71) MAPTESR1ESR2HPGDLMNA
SCHEMBL8071074 1.00 MAPT (0.71) MAPTESR1ESR2HPGDLMNA
SCHEMBL10486276 0.94 MAPT (0.64) MAPTESR1ESR2HPGDLMNA
SCHEMBL24421676 0.92 SRD5A2 (0.69) MAPTESR1ESR2HPGDLMNA
SCHEMBL18401385 0.92 SRD5A2 (0.69) MAPTESR1ESR2HPGDLMNA
SCHEMBL10669290 0.92 SRD5A2 (0.75) MAPTESR1ESR2HPGDLMNA
SCHEMBL24421578 0.92 SRD5A2 (0.69) MAPTESR1ESR2HPGDLMNA
SCHEMBL7938036 0.92 SRD5A2 (0.69) MAPTESR1ESR2HPGDLMNA
SCHEMBL19018299 0.90 LTA4H (0.73) MAPTESR1ESR2HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4731429-A Novel poly(aryl ether ketones) AMOCO CORPORATION (US) 1988-03-15 US claimed
JP-1065130-A None JP disclosed
JP-63152627-A None JP disclosed
JP-63312323-A None JP disclosed
CN-118325068-A Multielement copolymerization end-capped polyether ketone and preparation method thereof 吉林大学 2024-07-12 CN disclosed
EP-1857486-B1 Method for manufacturing polyarylene ether ketones EVONIK DEGUSSA GMBH (DE) 2013-12-04 EP disclosed
US-7786245-B2 Process for preparing polyarylene ether ketone EVONIK DEGUSSA GMBH (DE) 2010-08-31 US disclosed
WO-2009153100-A1 METHOD FOR PRODUCING POLYARYLENE ETHER KETONES EVONIK DEGUSSA GMBH (DE) 2009-12-23 WO disclosed
US-20080085990-A1 Method for Producing Polyarylene Ether Ketones DEGUSSA GMBH (DE) 2008-04-10 US disclosed
EP-1857486-A1 Method for manufacturing polyarylene ether ketones Evonik Degussa GmbH (DE) 2007-11-21 EP disclosed
US-4767838-A HIGH TEMPERATURE AND SOLVENT RESISTANT; HYDROQUINONE WITH A DIHALO OR DINITRO-BENZOPHENONE AND OTHER AROMATIC COMPOUND AMOCO CORPORATION (US) 1988-08-30 US disclosed
JP-S63152627-A AROMATIC POLYETHER KETONE AND PRODUCTION THEREOF ASAHI CHEM IND CO LTD 1988-06-25 JP disclosed
EP-0128692-B1 PROCESS FOR THE PREPARATION OF 4-HYDROXY-BENZOPHENONES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-03-02 EP disclosed
US-4687833-A HYDROQUINONE, 4,4'-DIHALO OR DINITRO KETONE, BASE, APROTIC SOLVENT AMOCO CORPORATION (US) 1987-08-18 US disclosed
EP-0231198-A1 CHAIN-EXTENDED POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1987-08-12 EP disclosed
EP-0226637-A1 CHAIN-EXTENDED POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1987-07-01 EP disclosed
WO-1987000539-A1 CHAIN-EXTENDED POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1987-01-29 WO disclosed
WO-1986007368-A1 CHAIN-EXTENDED POLY(ARYL ETHER KETONES) AMOCO CORPORATION (US) 1986-12-18 WO disclosed
US-4599452-A Chemical process IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-07-08 US disclosed
EP-0075390-A1 Production of arylophenones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-03-30 EP disclosed