Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 10/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13372950 | 0.82 | ALDH1A1 (0.37) | BRD4KMT2AALDH1A1POLBLPO | |
| SCHEMBL15332643 | 0.77 | — | — | |
| SCHEMBL2936291 | 0.77 | ALDH1A1 (0.46) | BRD4KMT2AALDH1A1POLBLPO | |
| SCHEMBL308400 | 0.76 | LPO (0.55) | BRD4KMT2AALDH1A1POLBMEN1 | |
| SCHEMBL4104820 | 0.74 | ESR1 (0.46) | ALDH1A1POLBESR1SMN1; SMN2KDM4E | |
| SCHEMBL31153305 | 0.73 | LPO (0.52) | BRD4KMT2AALDH1A1POLBLPO | |
| Hydrochloric Acid SCHEMBL1806963 | 0.73 | LPO (0.52) | BRD4KMT2AALDH1A1POLBLPO | |
| SCHEMBL24220236 | 0.72 | KMT2A (0.36) | BRD4KMT2AALDH1A1POLBMEN1 | |
| SCHEMBL7703330 | 0.71 | AGTR2 (0.34) | HPGDSMN1; SMN2PKM | |
| SCHEMBL15332849 | 0.70 | ALDH1A1 (0.45) | KMT2AALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8092662-B2 | Redox polymers | ABBOTT DIABETES CARE INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20090145757-A1 | Redox Polymers | ABBOTT DIABETES CARE INC. | 2009-06-11 | — | — | US | disclosed |