Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580730 | 0.81 | ALDH1A1 (0.46) | PPARGPPARAMEN1KMT2ASRR | |
| SCHEMBL4517205 | 0.81 | ALDH1A1 (0.46) | PPARGPPARAMEN1KMT2ASRR | |
| SCHEMBL20598268 | 0.81 | MEN1 (0.41) | CNR2MEN1KMT2AGLATDP1 | |
| SCHEMBL10404341 | 0.80 | ALDH1A1 (0.44) | PPARGPPARALMNASRRCYP1A2 | |
| SCHEMBL8376755 | 0.80 | ALDH1A1 (0.44) | PPARGPPARALMNASRRCYP1A2 | |
| SCHEMBL7052640 | 0.79 | MEN1 (0.40) | CNR2MEN1KMT2AGLATDP1 | |
| SCHEMBL7052644 | 0.79 | MEN1 (0.40) | CNR2MEN1KMT2AGLATDP1 | |
| SCHEMBL20598401 | 0.79 | MEN1 (0.40) | CNR2MEN1KMT2AGLATDP1 | |
| SCHEMBL7097856 | 0.79 | TDP1 (0.52) | CNR2KMT2AGLATDP1LMNA | |
| SCHEMBL1199677 | 0.79 | TDP1 (0.52) | CNR2KMT2AGLATDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | PPARG 1633/4885PPARA 1681/4885CNR2 1052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.