Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FADS1 | O60427 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28568899 | 0.88 | KLK7 (0.54) | KMT2AMEN1MAPTKLK7MTOR | |
| SCHEMBL28571893 | 0.88 | KLK7 (0.54) | KMT2AMEN1MAPTKLK7MTOR | |
| SCHEMBL10076917 | 0.87 | MAPT (0.50) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL27539120 | 0.81 | ALDH1A1 (0.51) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL25820324 | 0.80 | HPGD (0.68) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL27449199 | 0.80 | MTOR (0.61) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL27450197 | 0.80 | HPGD (0.72) | KMT2AMEN1MAPTHPGDALOX15 | |
| SCHEMBL10076825 | 0.79 | KMT2A (0.62) | KMT2AMEN1MAPTBCHEACHE | |
| SCHEMBL27539123 | 0.79 | TSHR (0.60) | KMT2AMEN1MAPT | |
| SCHEMBL8126585 | 0.79 | ALDH1A1 (0.52) | KMT2AMEN1MAPTGRM5LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |