Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GRM5 | P41594 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076815 | 0.87 | KMT2A (0.51) | MAPTMEN1KMT2AGRM5HPGD | |
| SCHEMBL28571893 | 0.86 | KLK7 (0.54) | MAPTMEN1KMT2AGRM5LPAR1 | |
| SCHEMBL28568899 | 0.86 | KLK7 (0.54) | MAPTMEN1KMT2AGRM5LPAR1 | |
| SCHEMBL8126585 | 0.84 | ALDH1A1 (0.52) | MAPTMEN1KMT2AGRM5ALDH1A1 | |
| SCHEMBL27539120 | 0.80 | ALDH1A1 (0.51) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL27450197 | 0.79 | HPGD (0.72) | MAPTMEN1KMT2AGRM5ALDH1A1 | |
| SCHEMBL27449199 | 0.79 | MTOR (0.61) | MAPTMEN1KMT2AGRM5HPGD | |
| SCHEMBL27539123 | 0.78 | TSHR (0.60) | MAPTMEN1KMT2AALDH1A1KCNK3 | |
| SCHEMBL10192111 | 0.77 | ALOX15 (0.69) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL11411034 | 0.77 | HSD17B10 (0.62) | MAPTMEN1KMT2AALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8106031-B2 | Hydrolytically-resistant boron-containing therapeutics and methods of use | ANACOR PHARMACEUTICALS, INC. (US) | 2012-01-31 | — | — | US | disclosed |