Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.58 |
| ▸ | CDK2 | P24941 | 5/20 | 0.58 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.58 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13037058 | 0.87 | CYP2C19 (0.46) | CDK1CDK2CCNE1CCNB1CYP2C19 | |
| SCHEMBL13037057 | 0.84 | TLR9 (0.42) | CDK1CDK2CCNE1CCNB1CYP2C19 | |
| SCHEMBL26036734 | 0.81 | CDK1 (0.67) | CDK1CDK2CCNE1CCNB1ADORA1 | |
| SCHEMBL19829082 | 0.76 | CCNE1 (0.73) | CDK1CDK2CCNE1CCNB1CYP2C19 | |
| SCHEMBL13751696 | 0.76 | CDK1 (0.58) | CDK1CDK2CCNE1CCNB1 | |
| SCHEMBL17860490 | 0.75 | CCNE1 (0.71) | CDK1CDK2CCNE1CCNB1CYP2C19 | |
| SCHEMBL19409223 | 0.75 | ADORA2A (0.36) | CDK1CDK2CCNE1CCNB1ADORA1 | |
| SCHEMBL27854926 | 0.75 | CDK1 (0.71) | CDK1CDK2CCNE1CCNB1HDAC1 | |
| SCHEMBL8767031 | 0.75 | CCNE1 (1.00) | CDK1CDK2CCNE1CCNB1CYP2C19 | |
| SCHEMBL20067187 | 0.70 | CDK2 (0.59) | CDK1CDK2CCNE1CCNB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012011114-A2 | SEQUENCE SPECIFIC DOUBLE-STRANDED DNA/RNA BINDING COMPOUNDS AND USES THEREOF | GENEARREST LTD (IL) | 2012-01-26 | — | — | WO | disclosed |