Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 4/20 | 0.67 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.67 |
| ▸ | CDK2 | P24941 | 3/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | YTHDC1 | Q96MU7 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13751696 | 0.81 | CDK1 (0.58) | CDK1CCNB1CCNE1CDK2PDE4D | |
| SCHEMBL10076896 | 0.81 | CDK1 (0.58) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL8767031 | 0.80 | CCNE1 (1.00) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL19829082 | 0.79 | CCNE1 (0.73) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL13828378 | 0.79 | YTHDC1 (0.66) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL27854926 | 0.78 | CDK1 (0.71) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL17860490 | 0.78 | CCNE1 (0.71) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL9582915 | 0.77 | MEN1 (0.56) | CDK1CCNB1CCNE1CDK2ADORA1 | |
| SCHEMBL9739894 | 0.77 | AXL (0.64) | ADORA1YTHDC1ADORA2APDE4APDE4B | |
| SCHEMBL9739023 | 0.76 | PDE4A (0.72) | ADORA1YTHDC1ADORA2APDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11738038-B2 | Highly active compounds against COVID-19 | Atea Pharmaceuticals, Inc. (US) | 2023-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11738038-B2 | Highly active compounds against COVID-19 | PNP, ACE2, MTAP | CDK1 1126/4885CCNB1 3082/4885CCNE1 3249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.