Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571217 | 0.88 | ESR1 (0.46) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL13673348 | 0.83 | CYP19A1 (0.38) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL2571819 | 0.76 | ESR1 (0.48) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL2570060 | 0.76 | ALOX15 (0.44) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL12052438 | 0.76 | ALOX12 (0.41) | ALOX12ALOX15MAPTKMT2AALDH1A1 | |
| SCHEMBL10042945 | 0.74 | ALOX12 (0.42) | ALOX12ALOX15MAPTKMT2AALDH1A1 | |
| SCHEMBL5856395 | 0.72 | PTPN1 (0.37) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL2570841 | 0.70 | ALOX15 (0.44) | ALOX12ALOX15MAPTKMT2AALDH1A1 | |
| SCHEMBL6769624 | 0.69 | ESR2 (0.72) | ESR1ESR2TTRALOX12ALOX15 | |
| SCHEMBL21780401 | 0.69 | ESR2 (0.72) | ESR1ESR2TTRALOX12ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407462-A1 | Substituted chroman derivatives, medicaments and use in therapy | Marshall Edwards, Inc. (US) | 2012-01-18 | — | — | EP | disclosed |