Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MPO | P05164 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16975858 | 1.00 | MEN1 (0.52) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL30135703 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL162554 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL29434606 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL29355137 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL29588649 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL200589 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL343309 | 0.88 | MAPT (0.54) | MEN1KMT2ALMNATSHRBLM | |
| Hydrochloric Acid SCHEMBL8995746 | 0.87 | MAPT (0.52) | MEN1KMT2ALMNATSHRBLM | |
| SCHEMBL8795420 | 0.87 | MAPT (0.49) | MEN1KMT2ALMNATSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021875-A1 | PEPTIDOMIMETIC MACROCYCLES WITH TRIAZOLE LINKERS | AILERON THERAPEUTICS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2012021874-A1 | PEPTIDOMIMETIC MACROCYCLES WITH THIOETHER LINKERS | AILERON THERAPEUTICS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |