Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162554 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL343309 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29434606 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29355137 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL200589 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29588649 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8995746 | 0.99 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6112940 | 0.99 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Metyrosine SCHEMBL2722717 | 0.90 | BLM (0.62) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10077124 | 0.88 | MEN1 (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319735-A1 | ENANTIOMER SELECTIVE ACTION ON NEUROTRANSMISSION | The Board of Trustees of the Leland Stanford Junior University (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117425472-A | Enantioselective action on neurotransmission | 小利兰·斯坦福大学托管委员会 | 2024-01-19 | — | — | CN | disclosed |
| WO-2022216543-A1 | ENANTIOMER SELECTIVE ACTION ON NEUROTRANSMISSION | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2022-10-13 | — | — | WO | disclosed |