Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343309 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL30135703 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29434606 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29355137 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL200589 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL29588649 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8995746 | 0.99 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6112940 | 0.99 | MAPT (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| Metyrosine SCHEMBL2722717 | 0.90 | BLM (0.62) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL10077124 | 0.88 | MEN1 (0.52) | MAPTMEN1KMT2AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3090 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250277012-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. | 2025-09-04 | — | — | US | claimed |
| CN-120157771-A | Incretin polypeptide analogue and application thereof | 北京诺尼瑞生物科技有限责任公司 | 2025-06-17 | — | — | CN | claimed |
| WO-2024206577-A1 | KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. (US) | 2024-10-03 | — | — | WO | claimed |
| US-20240226225-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | US | claimed |
| EP-4392440-A2 | COMBINATION OF RELAXIN AND VASOPRESSIN ANALOGUES FOR TREATMENT OF RENAL DISORDERS OR CONDITIONS | River 2 Renal Corp. (US) | 2024-07-03 | — | — | EP | claimed |
| US-20240209053-A1 | CONJUGATED HEPCIDIN MIMETICS | PROTAGONIST THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | US | claimed |
| US-20240197896-A1 | SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY | FELDAN BIO INC. (CA) | 2024-06-20 | — | — | US | claimed |
| CN-115919748-B | Prodrug-based stimulus response type nanogel and preparation method thereof | 复旦大学 | 2024-05-17 | — | — | CN | claimed |
| CN-117813313-A | Binding hepcidin mimetics | 领导医疗有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117750978-A | Synthetic peptide shuttle bioconjugates for intracellular cargo delivery | 费尔丹生物公司 | 2024-03-22 | — | — | CN | claimed |
| US-20030220521-A1 | Renal-selective prodrugs for control of renal sympathetic nerve activity in the treatment of hypertension | G.D. SEARLE & CO. | 2003-11-27 | — | — | US | claimed |
| EP-0484437-A4 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | SEARLE & CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0546123-A4 | — | — | 1994-04-27 | — | — | EP | claimed |
| EP-0546123-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| EP-0484437-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. Searle & Co. (US) | 1992-05-13 | — | — | EP | claimed |
| WO-1992004322-A1 | ALPHA-SUBSTITUTED TRYPTOPHANE DIPEPTOID DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1992-03-19 | — | — | WO | claimed |
| WO-1992001667-A1 | RENAL-SELECTIVE PRODRUGS FOR CONTROL OF RENAL SYMPATHETIC NERVE ACTIVITY IN THE TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-02-06 | — | — | WO | claimed |
| WO-1991001724-A1 | RENAL-SELECTIVE PRODRUGS FOR THE TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1991-02-21 | — | — | WO | claimed |
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | claimed |
| US-3988341-A | Esterification process | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | claimed |