SCHEMBL29355137

SCHEMBL29355137

C[C@](N)(Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
KDM4E B2RXH2 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
ALDH1A1 P00352 3/20 0.54
HPGD P15428 1/20 0.54
LMNA P02545 3/20 0.54
TSHR P16473 2/20 0.54
BLM P54132 2/20 0.54
APAF1 O14727 1/20 0.54
POLB P06746 1/20 0.54
RECQL P46063 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
MPO P05164 1/20 0.54
PMP22 Q01453 1/20 0.54
HIF1A Q16665 1/20 0.54
SLC6A2 P23975 1/20 0.51
FNTA P49354 1/20 0.51
FNTB P49356 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162554 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL343309 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL30135703 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL29434606 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL200589 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL29588649 1.00 MAPT (0.54) MAPTMEN1KMT2AKDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL8995746 0.99 MAPT (0.52) MAPTMEN1KMT2AKDM4ESMN1; SMN2
Hydrochloric Acid SCHEMBL6112940 0.99 MAPT (0.52) MAPTMEN1KMT2AKDM4ESMN1; SMN2
Metyrosine SCHEMBL2722717 0.90 BLM (0.62) MAPTMEN1KMT2AKDM4ESMN1; SMN2
SCHEMBL10077124 0.88 MEN1 (0.52) MAPTMEN1KMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727654-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
EP-4727655-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
EP-4727653-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF Mariana Oncology Inc. (US) 2026-04-22 EP claimed
US-20250186634-A1 METHODS OF TREATING SMALL CELL LUNG CANCER Evergreen Discovery, LLC (US) 2025-06-12 US claimed
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2025-05-15 US claimed
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-02-13 US claimed
US-20250034210-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-01-30 US claimed
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC (US) 2025-01-09 US claimed
WO-2024259115-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC. (US) 2024-12-19 WO claimed
WO-2024259147-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC. (US) 2024-12-19 WO claimed
WO-2024259132-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF MARIANA ONCOLOGY INC. (US) 2024-12-19 WO claimed
EP-4440592-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR Zealand Pharma A/S (DK) 2024-10-09 EP claimed
WO-2024206577-A1 KISSPEPTIN RECEPTOR (KISS1R) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-10-03 WO claimed
CN-118354781-A Peptide inhibitors of interleukin-23 receptor 西兰制药公司 2024-07-16 CN claimed
WO-2023099669-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR ZEALAND PHARMA A/S (DK) 2023-06-08 WO claimed
EP-4076541-A1 MODIFIED GRPR ANTAGONIST PEPTIDES FOR IMAGING AND THERAPY OF CANCER Technische Universität München (DE) 2022-10-26 EP claimed
CN-114845742-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2022-08-02 CN claimed
US-20220187315-A1 METHODS AND COMPOSITIONS FOR DIAGNOSING DEPRESSION DUKE UNIVERSITY 2022-06-16 US claimed
CN-122005879-A Modified GRPR antagonist peptides for cancer imaging and treatment 慕尼黑工业大学 2026-05-12 CN disclosed
WO-2022026629-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS, INC. (US) 2022-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049970-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDLIM5 MAPT 3952/4885MEN1 528/4885KMT2A 2586/4885
US-20250011368-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDCD1LG2 MAPT 3529/4885MEN1 488/4885KMT2A 2429/4885
US-20250186634-A1 METHODS OF TREATING SMALL CELL LUNG CANCER SSTR2, CCKBR, GRPR MAPT 4719/4885MEN1 54/4885KMT2A 1795/4885
US-20250034210-A1 DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF DLK1, DBNL, PDCD1LG2 MAPT 3529/4885MEN1 488/4885KMT2A 2429/4885
US-20250154198-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR IL23R, IL1RN, IL33 MAPT 1014/4885MEN1 3856/4885KMT2A 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.