Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 13/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077944 | 0.81 | CDK2 (0.33) | ESR1ESR2CDK2CDC25B | |
| SCHEMBL12999201 | 0.76 | LDHA (0.33) | NPSR1 | |
| SCHEMBL18785883 | 0.70 | ESR1 (0.57) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL14220068 | 0.69 | ESR1 (0.49) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL92373 | 0.69 | ESR1 (0.51) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL14477152 | 0.69 | ESR1 (0.48) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL10957911 | 0.68 | ESR1 (0.62) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL20274282 | 0.68 | ESR1 (0.52) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL12999208 | 0.68 | ESR1 (0.47) | ESR1ESR2KMT2AGAAMEN1 | |
| SCHEMBL18671983 | 0.67 | ESR1 (0.49) | ESR1ESR2KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2412733-A1 | Polymer, chemically amplified negative resist composition, and patterning process | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-02-01 | — | — | EP | disclosed |