SCHEMBL10077337

SCHEMBL10077337

OCCOCCOCCN1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
HRH3 Q9Y5N1 5/20 0.46
KDM4E B2RXH2 3/20 0.46
HTR1A P08908 1/20 0.45
MAPK1 P28482 2/20 0.43
TSHR P16473 1/20 0.43
ALDH1A1 P00352 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 1/20 0.41
CYP1A2 P05177 1/20 0.41
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10509584 0.98 HRH3 (0.48) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL12371260 0.98 MEN1 (0.50) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL10679639 0.98 MEN1 (0.50) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL17528474 0.98 MEN1 (0.50) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL4650639 0.98 HRH3 (0.48) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL1469605 0.96 TSHR (0.48) MEN1KMT2AHRH3KDM4EHTR1A
SCHEMBL22266158 0.92 HRH3 (0.48) HRH3KDM4EHTR1AMAPK1SMN1; SMN2
SCHEMBL18024038 0.89 HRH3 (0.53) HRH3MAPK1SMN1; SMN2CYP1A2
SCHEMBL31305372 0.89 MEN1 (0.55) MEN1KMT2AKDM4EHTR1AMAPK1
SCHEMBL31305373 0.89 MEN1 (0.55) MEN1KMT2AKDM4EHTR1AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3111940-B1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO LTD (CN) 2018-03-21 EP disclosed
US-9890181-B2 Silicon phthalocyanine complex, preparation method and medicinal application thereof SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO., LTD. (CN) 2018-02-13 US disclosed
US-9890181-B2 Silicon phthalocyanine complex, preparation method and medicinal application thereof SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO., LTD. (CN) 2018-02-13 US disclosed
EP-2598507-B1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI SA (FR) 2017-05-31 EP disclosed
US-20170002028-A1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO., LTD. (CN) 2017-01-05 US disclosed
US-20170002028-A1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF SHENZHEN CHINA RESOURCES GOSUN PHARMACEUTICAL CO., LTD. (CN) 2017-01-05 US disclosed
EP-3111940-A1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF Shenzhen China Resources Gosun Pharmaceutical Co., Ltd. (CN) 2017-01-04 EP disclosed
US-9056914-B2 Anticancer derivatives, preparation thereof and therapeutic use thereof SANOFI (FR) 2015-06-16 US disclosed
US-9056914-B2 Anticancer derivatives, preparation thereof and therapeutic use thereof SANOFI (FR) 2015-06-16 US disclosed
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-05-30 US disclosed
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2013-05-30 US disclosed
WO-2012014147-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170002028-A1 SILICON PHTHALOCYANINE COMPLEX, PREPARATION METHOD AND MEDICINAL APPLICATION THEREOF SRI, SCLY, PPIC MEN1 16/4885KMT2A 2055/4885HRH3 3573/4885
US-20130137659-A1 ANTICANCER DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF MCL1, TP53, MYC MEN1 1049/4885KMT2A 3275/4885HRH3 4686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.