Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563549 | 1.00 | HIF1A (0.57) | HIF1ACTBP2LMNASMN1; SMN2KDM1A | |
| SCHEMBL100774 | 1.00 | HIF1A (0.57) | HIF1ACTBP2LMNASMN1; SMN2KDM1A | |
| SCHEMBL17730475 | 0.92 | SLC22A2 (0.53) | HIF1ACTBP2LMNASMN1; SMN2KDM1A | |
| SCHEMBL21096339 | 0.87 | LMNA (0.53) | HIF1ACTBP2LMNASMN1; SMN2KDM1A | |
| SCHEMBL28911258 | 0.87 | LMNA (0.53) | HIF1ACTBP2LMNASMN1; SMN2KDM1A | |
| SCHEMBL5955216 | 0.81 | HIF1A (0.57) | HIF1ACTBP2LMNASMN1; SMN2CES2 | |
| SCHEMBL5955218 | 0.81 | HIF1A (0.57) | HIF1ACTBP2LMNASMN1; SMN2CES2 | |
| SCHEMBL10397502 | 0.80 | NPC1 (0.57) | ALDH1A1 | |
| SCHEMBL10397503 | 0.80 | NPC1 (0.57) | ALDH1A1 | |
| SCHEMBL21824482 | 0.80 | MEN1 (0.44) | HIF1ALMNASMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207872-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC Technology, INC. (US) | 2010-07-21 | — | — | EP | claimed |
| US-20090130849-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. | 2009-05-21 | — | — | US | claimed |
| WO-2009058274-A1 | CHEMICAL MECHANICAL POLISHING AND WAFER CLEANING COMPOSITION COMPRISING AMIDOXIME COMPOUNDS AND ASSOCIATED METHOD FOR USE | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | claimed |
| WO-2009058277-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC TECHNOLOGY, INC. (US) | 2009-05-07 | — | — | WO | claimed |
| US-20090111965-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | EKC TECHNOLOGY, INC. | 2009-04-30 | — | — | US | claimed |
| US-5821267-A | MODULATING THE INDUCIBLE ISOFORM OVER THE CONSTITUTIVE; HYPERTENSIVE, ANTIARTHRITIC AND DIABETIC AGENTS; THERAPY WITH CYTOKINES; TOXIC AND SEPTIC SHOCK | G.D. SEARLE & CO. (US) | 1998-10-13 | — | — | US | claimed |
| EP-0724435-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995011014-A1 | AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1995-04-27 | — | — | WO | claimed |
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| US-20260042731-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2026-02-12 | — | — | US | disclosed |
| US-20250388601-A1 | Compounds, Compositions and Methods | DENALI THERAPEUTICS INC. (US) | 2025-12-25 | — | — | US | disclosed |
| US-12435181-B2 | Formulations capable of reacting with or removal of molecular oxygen | LI SHENSHEN (US) | 2025-10-07 | — | — | US | disclosed |
| US-12358928-B2 | Compounds, compositions and methods | DENALI THERAPEUTICS INC. (US) | 2025-07-15 | — | — | US | disclosed |
| CN-119731146-A | (2, 4-Dichlorophenoxy) acetic acid analogues | 科迪华农业科技有限责任公司 | 2025-03-28 | — | — | CN | disclosed |
| WO-1984004676-A1 | POLYHYDROXYBENZOIC ACID DERIVATIVES | RIET BARTHOLOMEUS VAN T | 1984-12-06 | — | — | WO | disclosed |
| EP-0092706-A1 | Oxadiazole derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-11-02 | — | — | EP | disclosed |
| US-4308399-A | O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-12-29 | — | — | US | disclosed |
| US-4187220-A | New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1980-02-05 | — | — | US | disclosed |
| US-4134985-A | 5-CYCLOPROPANE CARBOXYLATE OXADIAZOLES AS INSECTICIDES AND ACARICIDES | STAUFFER CHEMICAL COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-3956498-A | SYNERGISTIC, INSECTICIDES | S. C. JOHNSON & SON, INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388601-A1 | Compounds, Compositions and Methods | AURKC, WEE2, ERBB2 | HIF1A 2807/4885CTBP2 3381/4885LMNA 581/4885 |
| US-12358928-B2 | Compounds, compositions and methods | PIK3CA, PLK1, PIK3CB | HIF1A 3501/4885CTBP2 2719/4885LMNA 1620/4885 |
| US-20260042731-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | DDT, AADAC, HACL2 | HIF1A 4386/4885CTBP2 3069/4885LMNA 1738/4885 |
| US-20090111965-A1 | NOVEL NITRILE AND AMIDOXIME COMPOUNDS AND METHODS OF PREPARATION | GNMT, NIT2, NNMT | HIF1A 2917/4885CTBP2 3759/4885LMNA 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.