Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1101870 | 0.90 | HTT (0.60) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL10078135 | 0.89 | HTT (0.61) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL1101566 | 0.86 | HTT (0.55) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL25085460 | 0.83 | ALDH1A1 (0.58) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL10077718 | 0.83 | HTT (0.58) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL13567688 | 0.82 | HTT (0.65) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL18120597 | 0.82 | KDM4E (0.71) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL24120058 | 0.80 | HTT (0.54) | HTTHIF1AARKDM4EMAPK1 | |
| SCHEMBL12266064 | 0.79 | HTT (0.61) | HTTHIF1AARKDM4EALDH1A1 | |
| SCHEMBL24083864 | 0.79 | AR (0.67) | HTTHIF1AARKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120160685-A1 | COATING LINE AND PROCESS FOR FORMING A MULTILAYER COMPONENT COATING ON A SUBSTRATE | PPG INDUSTRIES OHIO, INC. (US) | 2012-06-28 | — | — | US | disclosed |