Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NMT1 | P30419 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2843993 | 0.99 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3ROCK2HTR2C | |
| SCHEMBL10078522 | 0.81 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3ROCK2 | |
| Hydrochloric Acid SCHEMBL3576841 | 0.80 | SLC6A2 (0.40) | SLC6A4SLC6A2SLC6A3HTR2C | |
| Hydrochloric Acid SCHEMBL2840969 | 0.79 | SLC6A4 (0.36) | SLC6A4HTR2C | |
| Hydrochloric Acid SCHEMBL2840968 | 0.78 | HTR6 (0.31) | SLC6A4 | |
| SCHEMBL10078500 | 0.76 | PKM (0.31) | SLC6A4 | |
| SCHEMBL10078928 | 0.76 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL2841127 | 0.76 | PKM (0.30) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL2865940 | 0.75 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10078641 | 0.74 | HTR2C (0.33) | SLC6A4SLC6A2SLC6A3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | claimed |