Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2844088 | 0.99 | HTR2C (0.32) | HTR2CHTR2BSLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10078500 | 0.89 | PKM (0.31) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL2841127 | 0.88 | PKM (0.30) | SLC6A4 | |
| SCHEMBL10078712 | 0.86 | IMPDH2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL2835872 | 0.85 | IMPDH2 (0.39) | — | |
| SCHEMBL10078928 | 0.77 | SLC6A4 (0.40) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL2865940 | 0.76 | SLC6A4 (0.39) | SLC6A2SLC6A3SLC6A4 | |
| Hydrochloric Acid SCHEMBL2840969 | 0.76 | SLC6A4 (0.36) | HTR2CHTR2BSLC6A4 | |
| Hydrochloric Acid SCHEMBL2840968 | 0.75 | HTR6 (0.31) | SLC6A4 | |
| SCHEMBL10078545 | 0.74 | HTR2C (0.31) | HTR2CHTR2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | claimed |