Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 3/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2839303 | 0.99 | HTR2C (0.33) | GID4HTR2CHTR1AADRA2AADRA2B | |
| SCHEMBL10078734 | 0.85 | HTR6 (0.32) | GID4 | |
| Hydrochloric Acid SCHEMBL2840335 | 0.84 | HTR6 (0.31) | GID4 | |
| Hydrochloric Acid SCHEMBL2868875 | 0.78 | HTR2C (0.34) | HTR2CHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL10078522 | 0.78 | SLC6A2 (0.41) | HRH1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL2874228 | 0.77 | HTR2A (0.31) | HTR2C | |
| SCHEMBL10078515 | 0.77 | HTR2A (0.31) | HTR2C | |
| Hydrochloric Acid SCHEMBL3576841 | 0.77 | SLC6A2 (0.40) | HTR2CHRH1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2844093 | 0.76 | IMPDH2 (0.39) | — | |
| SCHEMBL10078688 | 0.76 | SLC6A4 (0.39) | HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217031-B2 | Heteroaryl derivatives | NIPPON SHINYAKU CO., LTD. (JP) | 2012-07-10 | — | — | US | claimed |