Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 7/20 | 0.80 |
| ▸ | LMNA | P02545 | 7/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.70 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.70 |
| ▸ | TSHR | P16473 | 5/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.70 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.70 |
| ▸ | SNCA | P37840 | 4/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.70 |
| ▸ | PGR | P06401 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | AR | P10275 | 3/20 | 0.70 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.70 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.70 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.70 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996696 | 0.96 | SHBG (0.75) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL1899376 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL4102864 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL4102861 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL13752654 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL1900826 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL1899372 | 0.89 | SHBG (1.00) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL18075707 | 0.88 | SHBG (0.80) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL601152 | 0.86 | LMNA (0.67) | SHBGLMNAHSD17B10SERPINA6TSHR | |
| SCHEMBL601153 | 0.86 | LMNA (0.67) | SHBGLMNAHSD17B10SERPINA6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051988-A2 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-04-26 | — | — | WO | disclosed |
| US-4898694-A | 17-Hydroxy-steroids | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1990-02-06 | — | — | US | disclosed |