Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057666 | 0.83 | CYP2D6 (0.35) | HRH3 | |
| SCHEMBL12305020 | 0.77 | EGFR (0.34) | EGFRMAPK9MAPK11HRH3CHRNA7 | |
| SCHEMBL5337601 | 0.72 | OPRD1 (0.36) | EGFRMAPK9MAPK11CHRNA7 | |
| SCHEMBL15540251 | 0.69 | HRH3 (0.40) | HRH3CHRNA7 | |
| SCHEMBL19507966 | 0.67 | GAA (0.33) | — | |
| SCHEMBL19012359 | 0.67 | NOS3 (0.33) | EGFRMAPK9MAPK11HRH3 | |
| SCHEMBL23089639 | 0.66 | OPRD1 (0.36) | EGFRMAPK9MAPK11 | |
| SCHEMBL29814792 | 0.66 | OPRD1 (0.36) | EGFRMAPK9MAPK11 | |
| SCHEMBL15265868 | 0.66 | CHRNA7 (0.34) | EGFRMAPK9MAPK11CHRNA7 | |
| SCHEMBL578244 | 0.65 | OPRM1 (0.55) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148404-B2 | Modulators of CB1 receptors | 7TM PHARMA A/S (DK) | 2012-04-03 | — | — | US | disclosed |
| US-20100144701-A1 | Modulators of CB1 Receptors | 7TM PHARMA A/S (DK) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144701-A1 | Modulators of CB1 Receptors | CNR1, CNR2, GPR6 | EGFR 495/4885MAPK9 936/4885MAPK11 1064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.