Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 20/20 | 0.49 |
| ▸ | MPEG1 | Q2M385 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10936786 | 0.86 | APAF1 (0.43) | ALOX5 | |
| SCHEMBL9326771 | 0.85 | ALDH1A1 (0.56) | — | |
| SCHEMBL15354650 | 0.79 | ALDH1A1 (0.62) | — | |
| SCHEMBL20098762 | 0.76 | ALDH1A1 (0.49) | ALOX5MPEG1 | |
| SCHEMBL21814446 | 0.73 | ACHE (0.51) | — | |
| SCHEMBL21814435 | 0.73 | ACHE (0.51) | — | |
| SCHEMBL21814546 | 0.73 | ACHE (0.51) | — | |
| SCHEMBL21814453 | 0.73 | ACHE (0.51) | — | |
| SCHEMBL21814442 | 0.73 | ACHE (0.51) | — | |
| SCHEMBL21818683 | 0.73 | ACHE (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012022467-A2 | NOVEL BENZOQUINONE DERIVATIVES AND USE THEREOF AS MODULATORS OF MITOCHONDRIAL FUNCTION | SANTHERA PHARMACEUTICALS (SCHWEIZ) AG (CH) | 2012-02-23 | — | — | WO | disclosed |