Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 8/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.37 |
| ▸ | ACACA | Q13085 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13263754 | 0.90 | ACACB (0.40) | BACE1SLC6A3ACACBACACADPP4 | |
| SCHEMBL10079517 | 0.82 | ACACB (0.55) | BACE1ACACBACACA | |
| SCHEMBL10079477 | 0.78 | ACACB (0.43) | BACE1ACACBACACA | |
| SCHEMBL10079513 | 0.74 | ACACB (0.33) | BACE1ACACBACACA | |
| SCHEMBL10079516 | 0.71 | GRM1 (0.32) | — | |
| SCHEMBL10079512 | 0.71 | CYP11B2 (0.39) | PTGS2 | |
| SCHEMBL14700752 | 0.66 | ACACB (0.74) | SLC6A3ACACBACACA | |
| SCHEMBL14689885 | 0.66 | ACACB (0.74) | SLC6A3ACACBACACA | |
| SCHEMBL2348234 | 0.66 | ACACB (0.74) | SLC6A3ACACBACACA | |
| SCHEMBL13817835 | 0.65 | HTT (0.43) | BACE1ACACBACACAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| US-8084649-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084649-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100173774-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173774-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| WO-2008110308-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | DDT, CYP19A1, RDX | BACE1 2668/4885SLC6A3 3823/4885ACACB 1253/4885 |
| US-20100173774-A1 | NOVEL HERBICIDES | DDT, HDHD5, HPD | BACE1 3529/4885SLC6A3 896/4885ACACB 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.