Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25567246 | 0.81 | ACHE (0.50) | S100A4MAPTTP53LMNARAB9A | |
| SCHEMBL1567503 | 0.81 | ACHE (0.58) | MAPTLMNAACHEKDM4EALDH1A1 | |
| SCHEMBL29850498 | 0.81 | ACHE (0.58) | MAPTLMNAACHEKDM4EALDH1A1 | |
| SCHEMBL31660734 | 0.81 | HTR2C (0.42) | S100A4MAPTTP53LMNACYP1A2 | |
| SCHEMBL5108272 | 0.81 | HTR2C (0.42) | S100A4MAPTTP53LMNACYP1A2 | |
| SCHEMBL4795033 | 0.80 | S100A4 (0.45) | S100A4MAPTTP53LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL6601125 | 0.79 | ACHE (0.56) | MAPTHTR2BACHEKDM4EALDH1A1 | |
| SCHEMBL16377312 | 0.74 | S100A4 (0.55) | S100A4MAPTTP53LMNACYP1A2 | |
| SCHEMBL1093630 | 0.74 | S100A4 (0.42) | S100A4MAPTTP53LMNACYP1A2 | |
| SCHEMBL5319357 | 0.74 | S100A4 (0.42) | S100A4MAPTTP53LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012018948-A2 | NOVEL TREATMENT OF PROSTATE CARCINOMA | PELLFICURE PHARMACEUTICALS, INC. (US) | 2012-02-09 | — | — | WO | disclosed |