SCHEMBL25567246

SCHEMBL25567246

COC1Cc2ccccc2-c2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 7/20 0.50
METAP1 P53582 2/20 0.42
TSHR P16473 1/20 0.42
HRH1 P35367 2/20 0.40
HRH4 Q9H3N8 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MAOA P21397 1/20 0.39
PTGS2 P35354 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 1/20 0.38
CYP19A1 P11511 2/20 0.38
S100A4 P26447 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1567503 0.93 ACHE (0.58) ACHEMETAP1TSHRHRH1HRH4
SCHEMBL29850498 0.93 ACHE (0.58) ACHEMETAP1TSHRHRH1HRH4
Hydrochloric Acid SCHEMBL6601125 0.91 ACHE (0.56) ACHEMETAP1TSHRHRH1HRH4
SCHEMBL10079528 0.81 S100A4 (0.53) ACHESMN1; SMN2NPC1TP53MAPT
SCHEMBL10412470 0.79 HRH1 (0.43) ACHEMETAP1TSHRHRH1HRH4
SCHEMBL9248465 0.77 ACHE (0.53) ACHEMETAP1TSHRSMN1; SMN2MAPT
SCHEMBL367345 0.75 KDM4E (0.55) ACHETSHRSMN1; SMN2NPC1MAPT
SCHEMBL9740101 0.75 ACHE (0.50) ACHEMETAP1TSHRHRH1MAPT
SCHEMBL15670682 0.74 ACHE (0.53) ACHEMETAP1TSHRHRH1MAPT
Bromide SCHEMBL15903300 0.74 KDM4E (0.54) ACHETSHRSMN1; SMN2NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof GENETIC INTELLIGENCE INC (US) 2023-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167447-A1 Compositions for FNIP1/FNIP2 Gene Modulation and Methods Thereof FNIP1, FN1, TNNC1 ACHE 3397/4885METAP1 3652/4885TSHR 3697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.