Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | APEX1 | P27695 | 2/20 | 0.67 |
| ▸ | RECQL | P46063 | 2/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.58 |
| ▸ | ESR1 | P03372 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796697 | 0.81 | CA12 (0.82) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL13805434 | 0.81 | KDM4E (0.80) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL29508368 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL941032 | 0.80 | KDM4E (1.00) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL2355138 | 0.75 | KDM4E (0.88) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL11218491 | 0.75 | CA12 (0.67) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL10079563 | 0.74 | KDM4E (0.51) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL940163 | 0.74 | CA12 (0.69) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL30608638 | 0.74 | RELA (1.00) | ALDH1A1KDM4EHPGDMEN1MAPT | |
| SCHEMBL941424 | 0.74 | RELA (1.00) | ALDH1A1KDM4EHPGDMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9093656-B2 | Quantum dots and hosts | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-9093656-B2 | Quantum dots and hosts | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130214249-A1 | QUANTUM DOTS AND HOSTS | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130214249-A1 | QUANTUM DOTS AND HOSTS | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| WO-2012013272-A1 | QUANTUM DOTS AND HOSTS | MERCK PATENT GMBH (DE) | 2012-02-02 | — | — | WO | disclosed |