Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626784 | 0.93 | GAA (0.52) | GAAKDM4AL3MBTL1GLSTSHR | |
| SCHEMBL13055397 | 0.84 | KDM4A (0.51) | GAAKDM4AL3MBTL1GLSTSHR | |
| SCHEMBL30313135 | 0.83 | GAA (0.47) | GAAKDM4AL3MBTL1TSHRNAMPT | |
| SCHEMBL22363679 | 0.83 | EPAS1 (0.48) | GAAKDM4AL3MBTL1TSHREPAS1 | |
| SCHEMBL30751415 | 0.83 | GAA (0.47) | GAAKDM4AL3MBTL1TSHRNAMPT | |
| SCHEMBL24971041 | 0.83 | GAA (0.47) | GAAKDM4AL3MBTL1TSHRNAMPT | |
| SCHEMBL1830157 | 0.81 | GLS (0.54) | KDM4AL3MBTL1GLSNAMPTIDO1 | |
| SCHEMBL23199572 | 0.81 | GAA (0.45) | GAAKDM4AL3MBTL1GLSTSHR | |
| SCHEMBL2542075 | 0.80 | L3MBTL1 (0.54) | GAAKDM4AL3MBTL1NAMPTHDAC1 | |
| SCHEMBL16532758 | 0.79 | GAA (0.48) | GAAKDM4AL3MBTL1TSHRNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020220-A1 | COMPOUNDS | NOVACTA BIOSYSTEMS LIMITED (GB) | 2012-02-16 | — | — | WO | disclosed |