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Sugi Predict / Compounds / SCHEMBL10079729

SCHEMBL10079729

SCHEMBL10079729

CCc1cc(C)cc(CC)c1C1=C(OC(=O)OCc2ccccc2)CC2(CCOCC2)CC1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ NPSR1 Q6W5P4 2/20 0.36
▸ EHMT2 Q96KQ7 1/20 0.34
▸ HSD17B10 Q99714 3/20 0.33
▸ MAPT P10636 3/20 0.33
▸ HTT P42858 2/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALDH1A1 P00352 3/20 0.33
▸ USP2 O75604 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ RAB9A P51151 3/20 0.32
▸ ATM Q13315 2/20 0.32
▸ STAT1 P42224 1/20 0.32
▸ POLB P06746 1/20 0.32
▸ GFER P55789 1/20 0.32
▸ PTGER1 P34995 1/20 0.32
▸ PTGER4 P35408 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10079732 0.89 EHMT2 (0.34) EHMT2HSD17B10ALDH1A1USP2TP53
SCHEMBL10079730 0.88 EHMT2 (0.30) MEN1KMT2AEHMT2MAPTKDM4E
SCHEMBL13263832 0.85 EHMT2 (0.33) EHMT2
SCHEMBL13263831 0.84 ALDH1A1 (0.37) MEN1KMT2ANPSR1EHMT2HSD17B10
SCHEMBL10079735 0.84 ALDH1A1 (0.30) LMNAALDH1A1TSHR
SCHEMBL10079734 0.84 EHMT2 (0.30) EHMT2
SCHEMBL10079708 0.83 NPSR1 (0.32) KMT2ANPSR1EHMT2ATMPOLB
SCHEMBL10079698 0.83 EHMT2 (0.31) EHMT2
SCHEMBL10079739 0.83 — —
SCHEMBL10079706 0.82 EHMT2 (0.30) EHMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487118-B2 Cyclic diones and their use as insecticides, acaricides and/or fungicides BAYER CROPSCIENCE AG (DE) 2013-07-16 — — US disclosed
US-8487118-B2 Cyclic diones and their use as insecticides, acaricides and/or fungicides BAYER CROPSCIENCE AG (DE) 2013-07-16 — — US disclosed
US-20120046464-A1 Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides BAYER CROPSCIENCE AG (DE) 2012-02-23 — — US disclosed
US-20120046464-A1 Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides BAYER CROPSCIENCE AG (DE) 2012-02-23 — — US disclosed
US-8084649-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2011-12-27 — — US disclosed
US-8084649-B2 Herbicides SYNGENTA CROP PROTECTION, INC. (US) 2011-12-27 — — US disclosed
US-20100173774-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-07-08 — — US disclosed
US-20100173774-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-07-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046464-A1 Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides DDT, CYP19A1, RDX MEN1 1087/4885KMT2A 2985/4885NPSR1 961/4885
US-20100173774-A1 NOVEL HERBICIDES DDT, HDHD5, HPD MEN1 4755/4885KMT2A 1123/4885NPSR1 2707/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.