Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079774 | 0.90 | ALDH1A1 (0.37) | ATMKDM4ERAD52ALDH1A1TSHR | |
| SCHEMBL13263633 | 0.84 | ALDH1A1 (0.31) | ALDH1A1TSHRBRD4 | |
| SCHEMBL10079733 | 0.82 | — | — | |
| SCHEMBL13263968 | 0.79 | ALDH1A1 (0.30) | ALDH1A1TSHR | |
| SCHEMBL10079778 | 0.77 | ALDH1A1 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL10079776 | 0.76 | ACACB (0.37) | KDM4EALDH1A1TSHRACACBBRD4 | |
| SCHEMBL10079476 | 0.76 | BRD4 (0.38) | ATMKDM4ERAD52ALDH1A1BRD4 | |
| SCHEMBL10079777 | 0.74 | ACACB (0.35) | ATMACACB | |
| SCHEMBL10079730 | 0.72 | EHMT2 (0.30) | KDM4E | |
| SCHEMBL10079713 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-8487118-B2 | Cyclic diones and their use as insecticides, acaricides and/or fungicides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | BAYER CROPSCIENCE AG (DE) | 2012-02-23 | — | — | US | disclosed |
| US-8084649-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-8084649-B2 | Herbicides | SYNGENTA CROP PROTECTION, INC. (US) | 2011-12-27 | — | — | US | disclosed |
| US-20100173774-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173774-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-07-08 | — | — | US | disclosed |
| WO-2008110308-A2 | NOVEL HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046464-A1 | Cyclic Diones and Their Use as Insecticides, Acaricides and/or Fungicides | DDT, CYP19A1, RDX | ATM 1870/4885KDM4E 1353/4885RAD52 1023/4885 |
| US-20100173774-A1 | NOVEL HERBICIDES | DDT, HDHD5, HPD | ATM 3868/4885KDM4E 756/4885RAD52 2317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.