Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818280 | 0.80 | HTT (0.42) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL954426 | 0.80 | HTT (0.39) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL29413826 | 0.76 | CFTR (0.37) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL255259 | 0.75 | GABRA1 (0.50) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL5713283 | 0.75 | HTT (0.44) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL29428538 | 0.75 | GABRA1 (0.50) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL10079990 | 0.74 | ADRB2 (0.44) | ALDH1A1CYP2C19CYP3A4CYP2C9IDO1 | |
| SCHEMBL11174670 | 0.74 | IDO1 (0.39) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL30172167 | 0.74 | APP (0.39) | HTTALDH1A1CYP2C19CYP3A4ALOX15 | |
| SCHEMBL4659907 | 0.73 | GABRA1 (0.48) | HTTALDH1A1CYP2C19CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012084678-A1 | NOVEL IMIDAZOLES USEFUL AS PLANT FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-06-28 | — | — | WO | disclosed |