Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15964700 | 0.83 | P2RY14 (0.59) | P2RY14KDM4EASPHRIOX2KDM8 | |
| SCHEMBL15964699 | 0.82 | P2RY14 (0.60) | P2RY14KDM4EASPHRIOX2KDM8 | |
| SCHEMBL360326 | 0.80 | LMNA (0.53) | P2RY14LMNAKMT2A | |
| SCHEMBL15964697 | 0.80 | P2RY14 (0.59) | P2RY14CNR1CNR2PTGER1 | |
| SCHEMBL17292023 | 0.79 | LMNA (0.55) | P2RY14LMNAKMT2A | |
| SCHEMBL15964701 | 0.76 | P2RY14 (0.52) | P2RY14CNR1CNR2LMNAPTGER1 | |
| SCHEMBL20388614 | 0.74 | HTR2C (0.64) | P2RY14PTGER4CNR1CNR2PTGER1 | |
| SCHEMBL16742700 | 0.73 | MARS1 (0.49) | P2RY14KDM4EHCAR2PTGER1 | |
| SCHEMBL18040417 | 0.73 | P2RY14 (0.46) | P2RY14KDM4EASPHRIOX2KDM8 | |
| SCHEMBL2323117 | 0.72 | HCAR3 (0.42) | P2RY14KDM4ECNR1CNR2HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008528-A1 | PYRAZOLE COMPOUND | 大日本住友製薬株式会社 (JP) | 2012-01-19 | — | — | WO | disclosed |