SCHEMBL10080392

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10079932	0.88	HTR2C (0.50)	HTR2CSLC6A4GLSALDH1A1GAA
	SCHEMBL10080809	0.80	HTR2C (0.44)	HTR2CSLC6A4GLSALDH1A1GAA
	SCHEMBL10080819	0.74	RIPK1 (0.40)	HTR2CSLC6A4ALDH1A1KMT2ARIPK1
	SCHEMBL7190668	0.74	RIPK1 (0.57)	HTR2CSLC6A4GLSCTSLCTSB
	SCHEMBL14924172	0.72	HTR2C (0.72)	HTR2CSLC6A4GLS
	SCHEMBL359249	0.72	ALDH1A1 (0.56)	ALDH1A1GAATHRBKMT2ANPC1
	SCHEMBL10080901	0.71	HTR2C (0.34)	HTR2CSLC6A4
	SCHEMBL10080295	0.70	HTR2C (0.42)	HTR2CSLC6A4KMT2AJAK2JAK1
	SCHEMBL23251855	0.70	HTR2C (0.48)	HTR2CSLC6A4ALDH1A1
	SCHEMBL10080808	0.70	HTR2C (0.33)	HTR2CSLC6A4ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.