Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707925 | 0.89 | TMPRSS4 (0.42) | MPLGRIK1DHODHMPOHPGD | |
| SCHEMBL29534764 | 0.82 | ALDH1A1 (0.45) | GRIK1DHODHMPOALDH1A1HPGD | |
| SCHEMBL8635085 | 0.82 | ALDH1A1 (0.45) | GRIK1DHODHMPOALDH1A1HPGD | |
| SCHEMBL10080476 | 0.81 | MEN1 (0.61) | MPLGRIK1DHODHMPOALDH1A1 | |
| SCHEMBL1758231 | 0.78 | MEN1 (0.66) | GRIK1DHODHALDH1A1HPGDHSD17B10 | |
| SCHEMBL8037442 | 0.72 | ALDH1A1 (0.58) | MPLGRIK1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8051763 | 0.72 | ALDH1A1 (0.54) | MPLGRIK1DHODHALDH1A1HPGD | |
| SCHEMBL4294298 | 0.71 | KDM4E (0.51) | GRIK1DHODHALDH1A1HPGDHSD17B10 | |
| SCHEMBL3902553 | 0.71 | GRIK1 (0.59) | GRIK1DHODHMPOALDH1A1HPGD | |
| SCHEMBL29978987 | 0.71 | GRIK1 (0.59) | GRIK1DHODHMPOALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012019106-A2 | POSITIVE AND NEGATIVE MODULATORS OF NMDA RECEPTORS | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2012-02-09 | — | — | WO | disclosed |