Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902553 | 1.00 | GRIK1 (0.59) | GRIK1LTB4RLTB4R2CYP2C8P2RX1 | |
| SCHEMBL23354390 | 0.91 | PTGDR2 (0.59) | GRIK1LTB4RLTB4R2CYP2C8TMPRSS4 | |
| SCHEMBL29978935 | 0.91 | PTGDR2 (0.59) | GRIK1LTB4RLTB4R2CYP2C8TMPRSS4 | |
| SCHEMBL6492505 | 0.89 | CYP2C8 (0.57) | GRIK1CYP2C8P2RX1P2RX4P2RX7 | |
| SCHEMBL23354157 | 0.87 | KDM4E (0.59) | LTB4RLTB4R2CYP2C8KDM1APTGDR2 | |
| SCHEMBL809394 | 0.85 | ALDH1A1 (0.59) | GRIK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL23354434 | 0.83 | CYP2C8 (0.54) | GRIK1LTB4RLTB4R2CYP2C8KDM1A | |
| SCHEMBL18223995 | 0.81 | KDM1A (0.54) | GRIK1CYP2C8KDM1AMPOALDH1A1 | |
| SCHEMBL6488781 | 0.81 | RXRA (0.54) | GRIK1CYP2C8KDM1AALDH1A1KDM4E | |
| SCHEMBL6800649 | 0.80 | PSEN1 (0.58) | LTB4RLTB4R2CYP2C8ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4058448-A1 | SUBSTITUTED HYDANTOINAMIDES AS ADAMTS7 ANTAGONISTS | Bayer Aktiengesellschaft (DE) | 2022-09-21 | — | — | EP | disclosed |