Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.65 |
| ▸ | EGFR | P00533 | 14/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 2/20 | 0.54 |
| ▸ | AURKA | O14965 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | INSR | P06213 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.53 |
| ▸ | FLT4 | P35916 | 1/20 | 0.53 |
| ▸ | CLK1 | P49759 | 1/20 | 0.53 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.53 |
| ▸ | TEK | Q02763 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | KIF5B | P33176 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15217642 | 0.91 | FBP1 (0.77) | FBP1EGFRERBB2ERBB4AURKA | |
| SCHEMBL12846249 | 0.89 | EGFR (0.64) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL10081608 | 0.89 | EGFR (0.62) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL26637 | 0.88 | FBP1 (0.84) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL30912752 | 0.88 | FBP1 (0.84) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL12641780 | 0.83 | EGFR (0.51) | FBP1EGFRERBB2ERBB4KDR | |
| SCHEMBL26350 | 0.81 | FBP1 (0.72) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL18633004 | 0.81 | EGFR (0.50) | FBP1EGFRERBB2AURKAKDR | |
| SCHEMBL18655505 | 0.80 | FBP1 (0.85) | FBP1EGFRERBB2ERBB4AURKA | |
| SCHEMBL14979614 | 0.80 | EGFR (0.71) | FBP1EGFRERBB2ERBB4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120165352-A1 | 6-AMINO QUINAZOLINE OR 3-CYANO QUINOLINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | SHANGHAI HENGRUI PHARMACEUTICAL CO., LTD. (CN) | 2012-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165352-A1 | 6-AMINO QUINAZOLINE OR 3-CYANO QUINOLINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL USES THEREOF | CSNK1G3, CSNK1A1, CSNK1A1L | FBP1 1316/4885EGFR 3299/4885ERBB2 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.