Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.39 |
| ▸ | NPY1R | P25929 | 10/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 9/20 | 0.39 |
| ▸ | NPY2R | P49146 | 6/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184339 | 0.90 | FOLH1 (0.39) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL2742864 | 0.86 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL24306834 | 0.86 | NPY4R (0.38) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL31589385 | 0.84 | TLR2 (0.42) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL6382960 | 0.84 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL1934309 | 0.81 | SIRT5 (0.49) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL24900018 | 0.81 | SIRT5 (0.49) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL30857468 | 0.81 | MMP1 (0.43) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL27113590 | 0.80 | NPY4R (0.41) | NPY4RNPY1RNPY5RNPY2RSIRT5 | |
| SCHEMBL25469335 | 0.80 | MEN1 (0.49) | NPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130085128-A1 | 6-(4-Hydroxy-phenyl)-3-alkyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | SANOFI (FR) | 2013-04-04 | — | — | US | disclosed |
| US-20120015936-A1 | SUBSTITUTED TETRAHYDRONAPHTHALENES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | SANOFI (FR) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085128-A1 | 6-(4-Hydroxy-phenyl)-3-alkyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors | MAP3K1, MAP3K6, MAP4K2 | NPY4R 1190/4885NPY1R 1539/4885NPY5R 1557/4885 |
| US-20120015936-A1 | SUBSTITUTED TETRAHYDRONAPHTHALENES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS DRUGS | PAH, MCHR1, DHPS | NPY4R 243/4885NPY1R 599/4885NPY5R 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.