Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS3 | P17931 | 3/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.47 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | LGALS1 | P09382 | 2/20 | 0.32 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12320208 | 1.00 | LGALS3 (0.47) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL15739307 | 1.00 | LGALS3 (0.47) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL10083815 | 1.00 | LGALS3 (0.47) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL24239531 | 0.90 | LGALS8 (0.43) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL17400171 | 0.90 | LGALS8 (0.43) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL24818885 | 0.86 | LGALS3 (0.54) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL19774686 | 0.86 | LGALS8 (0.45) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL24818847 | 0.86 | LGALS3 (0.54) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL22199891 | 0.86 | LGALS8 (0.45) | LGALS3LGALS8LGALS4SLC5A1PTPN1 | |
| SCHEMBL23025973 | 0.86 | LGALS8 (0.45) | LGALS3LGALS8LGALS4SLC5A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032829-A1 | POLY(VINYL ESTER) POLYMERS FOR IN VIVO NUCLEIC ACID DELIVERY | ARROWHEAD RESEARCH CORPORATION (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2012083046-A2 | GALACTOSE CLUSTER-PHARMACOKINETIC MODULATOR TARGETING MOIETY FOR SIRNA | ARROWHEAD RESEARCH CORPORATION (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2011104169-A1 | COMPOSITIONS FOR TARGETED DELIVERY OF SIRNA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-09-01 | — | — | WO | disclosed |