Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15385499 | 1.00 | MEN1 (0.52) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL459102 | 0.99 | MEN1 (0.51) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| SCHEMBL435831 | 0.95 | HSD11B1 (0.50) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| SCHEMBL15385492 | 0.95 | HSD11B1 (0.50) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL15380695 | 0.94 | HSD11B1 (0.49) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL434246 | 0.94 | HSD11B1 (0.49) | MEN1KMT2AHDAC4MAPK1SMN1; SMN2 | |
| SCHEMBL459246 | 0.87 | HSD11B1 (0.42) | MEN1KMT2ASMN1; SMN2HTTHSD11B1 | |
| SCHEMBL433057 | 0.87 | ROCK2 (0.48) | KMT2ASMN1; SMN2HTTHSD11B1LMNA | |
| SCHEMBL10083997 | 0.87 | NTSR1 (0.49) | HDAC4HSD11B1 | |
| SCHEMBL433056 | 0.87 | ROCK2 (0.48) | KMT2ASMN1; SMN2HTTHSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012410-A2 | KAPPA OPIOID RECEPTOR AGONISTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2012-01-26 | — | — | WO | disclosed |