SCHEMBL10084422

SCHEMBL10084422

CNC(=O)C(CCC(N)=O)NC

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ BMP1 P13497 3/20 0.51
▸ DPP4 P27487 1/20 0.40
▸ DPP8 Q6V1X1 1/20 0.40
▸ DPP9 Q86TI2 1/20 0.40
▸ KMT2A Q03164 2/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ PMP22 Q01453 1/20 0.39
▸ MMP2 P08253 4/20 0.33
▸ MMP9 P14780 4/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ CA2 P00918 4/20 0.33
▸ CA1 P00915 3/20 0.33
▸ ELANE P08246 1/20 0.31
▸ ANPEP P15144 1/20 0.31
▸ ENPEP Q07075 1/20 0.31
▸ FOLH1 Q04609 1/20 0.30
▸ MMP8 P22894 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21172264 1.00 BMP1 (0.51) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL14490962 0.83 KMT2A (0.41) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL16594959 0.83 KMT2A (0.41) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL18122802 0.83 KMT2A (0.41) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL11933753 0.82 BMP1 (0.55) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL23468491 0.81 BMP1 (0.56) BMP1ANPEPENPEPFOLH1MMP8
SCHEMBL13233708 0.81 KMT2A (0.40) BMP1DPP4DPP8DPP9KMT2A
SCHEMBL22300362 0.81 BMP1 (0.42) BMP1MMP2MMP9L3MBTL1ANPEP
SCHEMBL13218843 0.81 BMP1 (0.56) BMP1ANPEPENPEPFOLH1MMP8
SCHEMBL8139 0.81 KMT2A (0.50) BMP1DPP4DPP8DPP9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11827906-B2 Adeno-associated virus (AAV) clade f vector and uses therefor THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-11-28 — — US disclosed
US-20230287451-A1 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-09-14 — — US disclosed
US-20230265459-A1 Compositions Useful in Treatment of Spinal Muscular Atrophy THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-08-24 — — US disclosed
US-20230190966-A1 COMPOSITIONS USEFUL FOR TREATING GM1 GANGLIOSIDOSIS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-06-22 — — US disclosed
US-20230190966-A1 COMPOSITIONS USEFUL FOR TREATING GM1 GANGLIOSIDOSIS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-06-22 — — US disclosed
US-11578341-B2 Compositions useful in treatment of spinal muscular atrophy THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-02-14 — — US disclosed
US-20230040603-A1 COMPOSITIONS USEFUL FOR TREATING GM1 GANGLIOSIDOSIS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-02-09 — — US disclosed
US-20230002788-A1 AAV3B VARIANTS WITH IMPROVED PRODUCTION YIELD AND LIVER TROPISM THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2023-01-05 — — US disclosed
US-20220220453-A1 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2022-07-14 — — US disclosed
US-20220204990-A1 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2022-06-30 — — US disclosed
US-20200390888-A1 NOVEL AAV MEDIATED INFLUENZA VACCINES JANSSEN BIOTECH, INC. 2020-12-17 — — US disclosed
US-20200056205-A1 Compositions Useful in Treatment of Spinal Muscular Atrophy THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2020-02-20 — — US disclosed
US-20200056159-A1 NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2020-02-20 — — US disclosed
US-8119411-B2 Method for analyzing C-terminal amino acid sequence of peptide using mass spectrometry NEC CORPORATION (JP) 2012-02-21 — — US disclosed
WO-2012010516-A1 GROWTH HORMONE CONJUGATES NOVO NORDISK HEALTH CARE AG (CH) 2012-01-26 — — WO disclosed
US-20110183428-A1 METHOD FOR ANALYZING C-TERMINAL AMINO ACID SEQUENCE OF PEPTIDE USING MASS SPECTROMETRY NEC CORPORATION (JP) 2011-07-28 — — US disclosed
US-7879616-B2 Method for analyzing C-terminal amino acid sequence of peptide using mass spectrometry NEC CORPORATION (JP) 2011-02-01 — — US disclosed
US-7879616-B2 Method for analyzing C-terminal amino acid sequence of peptide using mass spectrometry NEC CORPORATION (JP) 2011-02-01 — — US disclosed
US-20100222547-A1 Integrated Photoactive Peptides and Uses Thereof MALLINCKRODT INC. 2010-09-02 — — US disclosed
US-20100197185-A1 LOW AND ULTRA-LOW FORMALDEHYDE EMISSION BINDERS FOR NON-WOVEN GLASS MAT SAINT-GOBAIN TECHNICAL FABRICS AMERICA, INC. 2010-08-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040603-A1 COMPOSITIONS USEFUL FOR TREATING GM1 GANGLIOSIDOSIS GALC, GBA1, GLA BMP1 1581/4885DPP4 2218/4885DPP8 554/4885
US-20200056159-A1 NOVEL ADENO-ASSOCIATED VIRUS (AAV) CLADE F VECTOR AND USES THEREFOR VSIG8, ASNS, FARSB BMP1 1151/4885DPP4 1710/4885DPP8 112/4885
US-20220204990-A1 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME ELAVL1, ELAVL3, ANKRD54 BMP1 3630/4885DPP4 3704/4885DPP8 2109/4885
US-20230265459-A1 Compositions Useful in Treatment of Spinal Muscular Atrophy SMN1; SMN2, SRP68, HNRNPH1 BMP1 2656/4885DPP4 4785/4885DPP8 3195/4885
US-20230190966-A1 COMPOSITIONS USEFUL FOR TREATING GM1 GANGLIOSIDOSIS GALC, GBA1, GBA2 BMP1 2860/4885DPP4 2953/4885DPP8 1889/4885
US-20200056205-A1 Compositions Useful in Treatment of Spinal Muscular Atrophy SMN1; SMN2, SRP68, HNRNPH1 BMP1 2656/4885DPP4 4785/4885DPP8 3195/4885
US-20100222547-A1 Integrated Photoactive Peptides and Uses Thereof DNPEP, PTMS, VIP BMP1 131/4885DPP4 38/4885DPP8 76/4885
US-11827906-B2 Adeno-associated virus (AAV) clade f vector and uses therefor ASNS, VSIG8, FARSB BMP1 933/4885DPP4 1734/4885DPP8 118/4885
US-20100197185-A1 LOW AND ULTRA-LOW FORMALDEHYDE EMISSION BINDERS FOR NON-WOVEN GLASS MAT FUS, WASF2, UFM1 BMP1 1819/4885DPP4 3867/4885DPP8 4108/4885
US-20200390888-A1 NOVEL AAV MEDIATED INFLUENZA VACCINES VSIR, VSIG8, IGLV6-57 BMP1 4036/4885DPP4 3730/4885DPP8 2667/4885
US-11578341-B2 Compositions useful in treatment of spinal muscular atrophy SMN1; SMN2, SRP68, HNRNPH1 BMP1 2656/4885DPP4 4785/4885DPP8 3195/4885
US-20230287451-A1 NOVEL AAV CAPSIDS AND COMPOSITIONS CONTAINING SAME ELAVL1, VSIG8, ELAVL3 BMP1 3634/4885DPP4 4057/4885DPP8 2289/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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