Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938181 | 0.90 | NPC1 (0.41) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL17980482 | 0.83 | KDM4E (0.34) | MAPTKDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL17980434 | 0.81 | KDM4E (0.38) | MAPTKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL16534179 | 0.81 | DPP4 (0.53) | GLAMAPTKDM4ENPC1RAB9A | |
| SCHEMBL498501 | 0.81 | DPP4 (0.53) | GLAMAPTKDM4ENPC1RAB9A | |
| SCHEMBL498575 | 0.81 | KDM4E (0.33) | GLAMAPTKDM4ENPC1RAB9A | |
| SCHEMBL12803325 | 0.78 | KDM4E (0.69) | GLAMAPTKDM4ENPC1RAB9A | |
| SCHEMBL19704638 | 0.75 | CYP3A4 (0.34) | — | |
| SCHEMBL19704635 | 0.75 | — | — | |
| SCHEMBL14198867 | 0.74 | PRMT6 (0.39) | MAPTKDM4ENPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773074-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2023-10-03 | — | — | US | disclosed |
| US-20210047285-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2021-02-18 | — | — | US | disclosed |
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2020-12-08 | — | — | US | disclosed |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-11 | — | — | US | disclosed |
| US-9847489-B1 | Polymer, method of preparing the same, and organic optoelectric device including the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2017-12-19 | — | — | US | disclosed |
| US-9716241-B2 | Polycyclic dithiophenes | BASF SE (DE) | 2017-07-25 | — | — | US | disclosed |
| US-9716241-B2 | Polycyclic dithiophenes | BASF SE (DE) | 2017-07-25 | — | — | US | disclosed |
| US-20160104849-A1 | POLYCYCLIC DITHIOPHENES | BASF SE (DE) | 2016-04-14 | — | — | US | disclosed |
| US-20160104849-A1 | POLYCYCLIC DITHIOPHENES | BASF SE (DE) | 2016-04-14 | — | — | US | disclosed |
| US-9233930-B2 | Polycyclic dithiophenes | BASF SE (DE) | 2016-01-12 | — | — | US | disclosed |
| US-9233930-B2 | Polycyclic dithiophenes | BASF SE (DE) | 2016-01-12 | — | — | US | disclosed |
| US-8436208-B2 | Substituted oligo- or polythiophenes | BASF SE (DE) | 2013-05-07 | — | — | US | disclosed |
| US-8436208-B2 | Substituted oligo- or polythiophenes | BASF SE (DE) | 2013-05-07 | — | — | US | disclosed |
| US-20120097935-A1 | POLYCYCLIC DITHIOPHENES | BASF SE (DE) | 2012-04-26 | — | — | US | disclosed |
| US-20110062426-A1 | SUBSTITUTED OLIGO- OR POLYTHIOPHENES | BASF SE (DE) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10858334-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | PPOX, TST, COX6C | GLA 4743/4885MAPT 4271/4885KDM4E 3896/4885 |
| US-11773074-B2 | Method for aerobic oxidative coupling of thiophenes with a ligand-supported palladium catalyst | PPOX, TST, COX6C | GLA 4743/4885MAPT 4271/4885KDM4E 3896/4885 |
| US-20190210993-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | PPOX, TST, COX6C | GLA 4743/4885MAPT 4271/4885KDM4E 3896/4885 |
| US-20110062426-A1 | SUBSTITUTED OLIGO- OR POLYTHIOPHENES | MRPL38, SLC39A7, SLC39A14 | GLA 1025/4885MAPT 1272/4885KDM4E 2266/4885 |
| US-20160104849-A1 | POLYCYCLIC DITHIOPHENES | C1R, C2CD5, CBR3 | GLA 4696/4885MAPT 3959/4885KDM4E 873/4885 |
| US-20210047285-A1 | Method for Aerobic Oxidative Coupling of Thiophenes with a Ligand-Supported Palladium Catalyst | PPOX, TST, COX6C | GLA 4743/4885MAPT 4271/4885KDM4E 3896/4885 |
| US-20120097935-A1 | POLYCYCLIC DITHIOPHENES | C1R, IPO5, C2CD5 | GLA 4781/4885MAPT 3326/4885KDM4E 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.