Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10085248 | 0.88 | PTGER4 (0.49) | HDAC3HDAC1HDAC8HDAC6PTGER4 | |
| SCHEMBL12900455 | 0.86 | HDAC3 (0.42) | ALDH1A1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL12585200 | 0.77 | PTGER4 (0.51) | HDAC3HDAC1HDAC8HDAC6PTGER4 | |
| SCHEMBL12583785 | 0.75 | HDAC3 (0.44) | ALDH1A1HDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL12583769 | 0.75 | RAB9A (0.49) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL12585207 | 0.75 | PTGER4 (0.54) | PTGER4 | |
| SCHEMBL988503 | 0.74 | EGFR (0.46) | MAPTSMN1; SMN2 | |
| SCHEMBL12583797 | 0.73 | DRD2 (0.47) | ALDH1A1HDAC1MEN1KMT2APTGER4 | |
| SCHEMBL12948806 | 0.71 | GAA (0.51) | ALDH1A1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL10085255 | 0.71 | CAPN1 (0.46) | ALDH1A1MEN1KMT2AGPR139THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460787-A1 | Amide compounds and their use as PGE2 antagonists. | Astellas Pharma Inc. (JP) | 2012-06-06 | — | — | EP | disclosed |
| US-20110028463-A1 | AMIDE COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028463-A1 | AMIDE COMPOUNDS | PTGER4, PTGER1, PTGER2 | ALDH1A1 2220/4885HDAC3 306/4885HDAC1 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.