Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 11/20 | 0.51 |
| ▸ | CA2 | P00918 | 11/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | PLEC | Q15149 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082268 | 0.88 | CA9 (0.50) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL10082261 | 0.87 | USP2 (0.56) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL10145544 | 0.82 | USP2 (0.55) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL16124797 | 0.81 | CA9 (0.77) | CA9CA1CA2USP2L3MBTL1 | |
| SCHEMBL3430200 | 0.79 | USP2 (0.74) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL10082263 | 0.78 | SOS1 (0.49) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL29781098 | 0.78 | USP2 (0.76) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL29591827 | 0.78 | USP2 (0.76) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL107875 | 0.78 | USP2 (0.76) | DNASE1L3PRMT1CA9CA1CA2 | |
| SCHEMBL8947940 | 0.77 | USP2 (0.58) | DNASE1L3PRMT1CA9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | Cercacor Laboratories, Inc (US) | 2014-05-08 | — | — | US | disclosed |
| US-8466286-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | MASIMO LABORATORIES, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8029765-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-10-04 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-8008088-B2 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | MASIMO LABORATORIES, INC. (US) | 2011-08-30 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | MASIMO LABORATORIES, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | CERCACOR LABORATORIES, INC. | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127137-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | DNASE1L3 3107/4885PRMT1 2110/4885CA9 585/4885 |
| US-20070110672-A1 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors | GCKR, SYMPK, SUCNR1 | DNASE1L3 3107/4885PRMT1 2110/4885CA9 585/4885 |
| US-20120052018-A1 | SMMR (SMALL MOLECULE METABOLITE REPORTERS) FOR USE AS IN VIVO GLUCOSE BIOSENSORS | GCKR, SYMPK, SUCNR1 | DNASE1L3 3107/4885PRMT1 2110/4885CA9 585/4885 |
| US-20090004108-A1 | Smmr (Small Molecule Metabolite Reporters) For Use As In Vivo Glucose Biosensors | GCKR, SYMPK, SUCNR1 | DNASE1L3 3107/4885PRMT1 2110/4885CA9 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.