Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 5/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 1/20 | 0.58 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALPL | P05186 | 1/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.56 |
| ▸ | PLEC | Q15149 | 1/20 | 0.54 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 8/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968894 | 0.88 | USP2 (0.65) | USP2L3MBTL1ABCB1ATMCFTR | |
| SCHEMBL7970059 | 0.87 | USP2 (0.76) | USP2L3MBTL1ABCB1ATMCFTR | |
| SCHEMBL458205 | 0.87 | ABCB1 (0.77) | USP2L3MBTL1ABCB1ATMCFTR | |
| SCHEMBL107875 | 0.87 | USP2 (0.76) | USP2L3MBTL1ATMPOLBMEN1 | |
| SCHEMBL29781098 | 0.87 | USP2 (0.76) | USP2L3MBTL1ATMPOLBMEN1 | |
| SCHEMBL29591827 | 0.87 | USP2 (0.76) | USP2L3MBTL1ATMPOLBMEN1 | |
| SCHEMBL8947940 | 0.87 | USP2 (0.58) | USP2L3MBTL1ABCB1ATMPOLB | |
| Hydrochloric Acid SCHEMBL5606345 | 0.86 | USP2 (0.76) | USP2L3MBTL1ABCB1ATMCFTR | |
| Hydrochloric Acid SCHEMBL29376502 | 0.86 | USP2 (0.76) | USP2L3MBTL1ABCB1ATMCFTR | |
| SCHEMBL7959938 | 0.86 | USP2 (0.68) | USP2L3MBTL1ABCB1ATMCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230175036-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | ENZO LIFE SCIENCES, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230175036-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | ENZO LIFE SCIENCES, INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-11661621-B2 | Self-immolative probes for enzyme activity detection | ENZO LIFE SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-11661621-B2 | Self-immolative probes for enzyme activity detection | ENZO LIFE SCIENCES, INC. (US) | 2023-05-30 | — | — | US | disclosed |
| US-11028121-B2 | Multisignal labeling reagents and processes and uses therefor | ENZO LIFE SCIENCES, INC. (US) | 2021-06-08 | — | — | US | disclosed |
| US-10920265-B2 | Compounds and methods for detection of enzymes that remove methyl succinyl groups from epsilon-amino lysine moieties | ENZO LIFE SCIENCES, INC. (US) | 2021-02-16 | — | — | US | disclosed |
| US-20200291448-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | ENZO LIFE SCIENCES, INC. (US) | 2020-09-17 | — | — | US | disclosed |
| US-20200283821-A1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE METHYL SUCCINYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES | ENZO LIFE SCIENCES, INC. (US) | 2020-09-10 | — | — | US | disclosed |
| US-20200270297-A1 | MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR | ENZO LIFE SCIENCE, INC. (US) | 2020-08-27 | — | — | US | disclosed |
| US-10718005-B2 | Self-immolative probes for enzyme activity detection | Enzo Life Sciences, Inc (US) | 2020-07-21 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | MERCK SHARP & DOHME CORP. | 2009-06-18 | — | — | US | disclosed |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | US | disclosed |
| WO-2009046165-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | EPOCH BIOSCIENCES, INC. (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | EPOCH BIOSCIENCES, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | EPOCH BIOSCIENCES, INC. (US) | 2007-07-26 | — | — | US | disclosed |
| US-6229055-B1 | SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES | MOLECULAR PROBES, INC. | 2001-05-08 | — | — | US | disclosed |
| US-6162931-A | Fluorinated xanthene derivatives | MOLECULAR PROBES, INC. (US) | 2000-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207887-A1 | PHOSPHONYLATED FLUORESCENT DYES AND CONJUGATES | PHOSPHO1, PFAS, PHPT1 | USP2 3043/4885L3MBTL1 3041/4885ABCB1 1504/4885 |
| US-20090156825-A1 | Fluorescent compounds that bind to histone deacetylase | HDAC1, HDAC3, HDAC11 | USP2 2116/4885L3MBTL1 1410/4885ABCB1 4214/4885 |
| US-20070172832-A1 | Phosphonate fluorescent dyes and conjugates | PHOSPHO1, PFAS, PHPT1 | USP2 3531/4885L3MBTL1 2908/4885ABCB1 989/4885 |
| US-20230175036-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | SORD, SI, IMMT | USP2 2113/4885L3MBTL1 1141/4885ABCB1 4537/4885 |
| US-11661621-B2 | Self-immolative probes for enzyme activity detection | MGAM, SI, ENGASE | USP2 1352/4885L3MBTL1 965/4885ABCB1 4574/4885 |
| US-20200291448-A1 | SELF-IMMOLATIVE PROBES FOR ENZYME ACTIVITY DETECTION | MGAM, SI, ENGASE | USP2 1352/4885L3MBTL1 965/4885ABCB1 4574/4885 |
| US-20200283821-A1 | COMPOUNDS AND METHODS FOR DETECTION OF ENZYMES THAT REMOVE METHYL SUCCINYL GROUPS FROM EPSILON-AMINO LYSINE MOIETIES | EMG1, SPR, SHMT1 | USP2 606/4885L3MBTL1 1693/4885ABCB1 4643/4885 |
| US-20090093612-A1 | AMIDE-SUBSTITUTED XANTHENE DYES | ANXA5, PHOSPHO1, TPST2 | USP2 3838/4885L3MBTL1 4614/4885ABCB1 4256/4885 |
| US-10718005-B2 | Self-immolative probes for enzyme activity detection | MGAM, SI, ENGASE | USP2 1352/4885L3MBTL1 965/4885ABCB1 4574/4885 |
| US-10920265-B2 | Compounds and methods for detection of enzymes that remove methyl succinyl groups from epsilon-amino lysine moieties | EMG1, SPR, SHMT1 | USP2 606/4885L3MBTL1 1693/4885ABCB1 4643/4885 |
| US-11028121-B2 | Multisignal labeling reagents and processes and uses therefor | PCNA, LIG4, LIG1 | USP2 3508/4885L3MBTL1 1074/4885ABCB1 3982/4885 |
| US-20200270297-A1 | MULTISIGNAL LABELING REAGENTS AND PROCESSES AND USES THEREFOR | PCNA, LIG4, LIG1 | USP2 3508/4885L3MBTL1 1074/4885ABCB1 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.