Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284221 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| SCHEMBL178498 | 1.00 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL26650359 | 0.98 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL26650364 | 0.98 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| Hydrochloric Acid SCHEMBL29532516 | 0.98 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| SCHEMBL30606202 | 0.84 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| SCHEMBL28277824 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| SCHEMBL2669165 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL10087160 | 0.78 | POLB (0.47) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA | |
| SCHEMBL508662 | 0.78 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2POLBCYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541592-B2 | Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 | AMGEN INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-8124634-B2 | CB1 receptor modulators | 7TM PHARMA A/S (DK) | 2012-02-28 | — | — | US | disclosed |
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | 7TM PHARMA A/S (DK) | 2010-01-14 | — | — | US | disclosed |
| US-20070197598-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | AMGEN INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197598-A1 | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 71/4885SMN1; SMN2 2512/4885POLB 669/4885 |
| US-20100010061-A1 | CB1 RECEPTOR MODULATORS | CNR1, CNR2, GPR6 | ALDH1A1 3325/4885SMN1; SMN2 3896/4885POLB 4193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.