Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10087271 | 0.89 | L3MBTL1 (0.46) | CYP1A1POLBL3MBTL1CA12CA1 | |
| SCHEMBL10087260 | 0.85 | CA1 (0.36) | POLBKMT2ACA12CA1CA2 | |
| SCHEMBL3015460 | 0.82 | CYP1A1 (0.54) | CYP1A1POLBBCHEL3MBTL1MAPT | |
| SCHEMBL13622824 | 0.82 | SMN1; SMN2 (0.42) | CYP1A1POLBL3MBTL1MAPTKMT2A | |
| SCHEMBL13578707 | 0.81 | CA1 (0.41) | MAPTKMT2ACA12CA1CA2 | |
| SCHEMBL10382417 | 0.76 | ALDH1A1 (0.51) | POLBMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13100287 | 0.74 | CA1 (0.36) | CA12CA1CA2CA4CA9 | |
| SCHEMBL12350707 | 0.73 | MAP4K4 (0.40) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL12350692 | 0.73 | NAMPT (0.37) | L3MBTL1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL90903 | 0.72 | NPC1 (0.41) | MAPTKMT2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114381-B2 | Radiolabeled compounds and compositions, their precursors and methods for their production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2012-02-14 | — | — | US | disclosed |
| US-20080038191-A1 | Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080038191-A1 | Radiolabeled Compounds And Compositions, Their Precursors And Methods For Their Production | GMNN, MEN1, NCLN | CYP1A1 3561/4885POLB 408/4885BCHE 2180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.