SCHEMBL10691315

SCHEMBL10691315

CCN(CC)S(=O)(=O)c1cc(Cl)c(N)cc1Cl

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
SMN1; SMN2 Q16637 5/20 0.51
KMT2A Q03164 1/20 0.51
TSHR P16473 6/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
MCOLN3 Q8TDD5 1/20 0.48
NPSR1 Q6W5P4 3/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 1/20 0.43
KDM4E B2RXH2 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689995 0.88 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL11700687 0.87 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL11518719 0.85 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL10687962 0.84 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL10694944 0.82 TSHR (0.41) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL3844818 0.82 VCAM1 (0.46) ALDH1A1SMN1; SMN2KMT2ANPSR1
SCHEMBL11283353 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL1008822 0.80 ALDH1A1 (0.79) ALDH1A1KMT2ATSHRMAPTCA12
SCHEMBL11685789 0.80 MCOLN3 (0.59) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2
SCHEMBL11685852 0.80 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2KMT2ATSHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4754024-A Fibre-reactive azo dyes containing vinylsulfonyl or analogous groups CIBA-GEIGY CORPORATION 1988-06-28 US disclosed
US-4207233-A Azo dyes containing a thiazole component BASF AKTIENGESELLSCHAFT (DE) 1980-06-10 US disclosed
US-4060521-A POLYAMIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed
US-4046756-A HYDROPHOBIC TEXTILES SANDOZ LTD. (CH) 1977-09-06 US disclosed
US-4026931-A AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed