SCHEMBL1921886

SCHEMBL1921886

Oc1ccccc1Nc1ccc(-c2ccc(Nc3ccccc3O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.53
MAPT P10636 9/20 0.46
GAA P10253 9/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPK1 P28482 3/20 0.46
RECQL P46063 3/20 0.46
HTT P42858 3/20 0.46
ABCB1 P08183 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
KDM4E B2RXH2 5/20 0.42
HPGD P15428 3/20 0.42
BLM P54132 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
ALOX15 P16050 3/20 0.42
HSD17B10 Q99714 3/20 0.42
TP53 P04637 2/20 0.42
APP P05067 1/20 0.42
SNCA P37840 1/20 0.42
TDP1 Q9NUW8 5/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1920750 0.93 CXCR2 (0.59) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL6760764 0.86 MAPT (0.55) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL11000813 0.86 CXCR2 (0.63) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL29720861 0.86 CXCR2 (0.68) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL1008928 0.86 CXCR2 (0.68) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL27435565 0.84 CXCR2 (0.66) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL13286497 0.83 CXCR2 (0.41) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL30686692 0.83 MAPT (0.60) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL28291094 0.83 CXCR2 (0.50) CXCR2MAPTGAAMEN1KMT2A
SCHEMBL9566028 0.83 CXCR2 (0.50) CXCR2MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1528074-B1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF TOSOH CORP (JP) 2014-03-26 EP disclosed
EP-2327739-A1 Novel triarylamine polymer, process for its production and its use TOSOH CORPORATION (JP) 2011-06-01 EP disclosed
US-7608680-B2 Triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2009-10-27 US disclosed
US-20060241278-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2006-10-26 US disclosed
US-20060017040-A9 Novel triarylamine polymer, process for producing the same, and use thereof SUZUKI TAKAO 2006-01-26 US disclosed
EP-1528074-A1 NOVEL TRIARYLAMINE POLYMER, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF Tosoh Corporation (JP) 2005-05-04 EP disclosed
US-20040262574-A1 Novel triarylamine polymer, process for producing the same, and use thereof TOSOH CORPORATION (JP) 2004-12-30 US disclosed